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A mobile genetic unit called a Retrotransposon insertion in premelanosome protein (PMEL17) or silver locus protein homolog (SILV) is responsible for Merle patterning in a number of domestic dog breeds. Merle is actually a heterozygote of an incompletely dominant gene. 

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1 hour ago, socks said:

A mobile genetic unit called a Retrotransposon insertion in premelanosome protein (PMEL17) or silver locus protein homolog (SILV) is responsible for Merle patterning in a number of domestic dog breeds. Merle is actually a heterozygote of an incompletely dominant gene. 

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